BIOT239 — Biomaterials and Tissue Engineering
BIOT 239 - Biomaterials and Tissue Engineering BIOT 239 - Biomaterials and Tissue Engineering Topics to be considered include biomaterial scaffolds, relevant cell types, soluble regulators or their genes, and mechanical loading and culture conditions. Comparisons will be made between differentiated cell types and stem cells as well as natural and synthetic scaffolds. Methodology for the preparation of cells and scaffolds in practice is described. The rationale for employing growth factors is covered and the techniques for gene modification for optimizing matrix interactions are discussed. Methods for fabricating tissue- engineered products and devices for implantation are taught including material selection and processing, mechanisms of material degradation, cell-material interactions and interfaces, matrix structure transport issues. Examples of tissue engineering -based procedures currently employed clinically are analyzed as case studies. Students will gain experience with biomaterial design and modification in addition to cell culture with these matrices. MAJOR COURSE LEARNING
Prerequisites: BIOT201